The ideal injection frequency depends on your dose, individual response, and how your body metabolizes testosterone. At a minimum, twice per week (every 3.5 days) is recommended to maintain stable levels and reduce fluctuations. Many men prefer 3x per week or daily injections for even smoother hormone balance, especially if they experience side effects like mood swings, water retention, or fatigue on less frequent dosing.
Testosterone has a half-life, meaning levels rise after an injection and then gradually decline. Injecting once per week or less can lead to peaks and crashes, causing inconsistent energy, mood, and libido. More frequent injections help minimize these fluctuations and often improve symptom control.
If you’re new to TRT, starting with 2-3 injections per week is a good approach, with adjustments based on how you feel. Some men do well with daily microdosing, while others feel fine with 2-3x per week. The key is finding what works best for your body while keeping levels stable.