Testosterone injections can be done using either intramuscular (IM) or subcutaneous (SubQ) methods, depending on your preference and how your body responds. Intramuscular injections deliver testosterone deep into the muscle, typically using a 25-27 gauge needle, 1-1.5 inches long, injected into the quads, glutes, or delts. The quad (vastus lateralis) is a popular site because it’s easy to reach, requires minimal flexibility, and provides good absorption.
Subcutaneous injections involve injecting testosterone into the fat layer under the skin, often using a 27-29 gauge needle, 0.5 to 0.75 inch long. The most common injection sites are the abdomen or upper thigh, where fat is easily pinched. Many men prefer SubQ because it requires a smaller needle, is less painful, and can lead to smoother hormone levels with fewer estrogen spikes. However, absorption rates may vary between individuals.
Regardless of the method, proper sterile injection technique is crucial. Always use a new needle and rotate injection sites to prevent scar tissue buildup. If you’re new to injections, it may take time to get comfortable, but following proper technique minimizes discomfort and improves consistency. For a full demo of both IM and SubQ injection techniques, see our Injection Guides for TRT.