Not necessarily. Many men on TRT see their hematocrit rise to 54-57% without issues, and donating blood too frequently can lead to low iron, fatigue, and reduced oxygen delivery.
Blood donation should only be considered if you have symptoms like dizziness, headaches, or high blood pressure, and other blood markers (like platelets, ferritin, and viscosity) suggest a real risk. Hydration, managing iron intake, and proper monitoring are often enough to keep hematocrit in check without unnecessary donations.
If you’re unsure whether blood donation is needed, work with a TRT-literate doctor rather than donating reflexively. For more details, see The Ultimate Guide To Hematocrit On TRT.
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